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Filtered Search Results
Medchemexpress LLC HY-103015 1mg Medchemexpress, WZ4141 CAS:1222776-76-2 Purity:>98%
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Medchemexpress, HY-103015 1mg WZ4141 CAS:1222776-76-2 WZ4141 is an API intermediate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | C25H27ClF3N5O3 | 10MG
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PND-1186 hydrochloride is the hydrochloride salt of a potent, selective, and reversible focal adhesion kinase (FAK) inhibitor supplied for laboratory research. It exhibits nanomolar potency (IC50 = 1.5 nM) and selectively promotes tumor cell apoptosis. Supplied as a high-purity solid with defined solubility and storage recommendations for controlled experimental use.
- Potent FAK inhibition with IC50 of 1.5 nM.
- High purity (99.9%).
- Molecular formula C25H27ClF3N5O3; molecular weight 537.96.
- Soluble in DMSO (100 mg/mL) and water (20 mg/mL).
- Recommended storage: 4°C for solid; in solvent -80°C up to 6 months.
- Intended for research use only; not for human or veterinary use.
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Medchemexpress LLC O-desmethyl galanthamine | 60755-80-8 | MFCD07369289 | 99.7% | C16H19NO3 | 10MG
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O-desmethyl galanthamine (sanguinine) is a galanthamine-type alkaloid used as a research reagent and reference standard. It acts as a reversible acetylcholinesterase (AChE) inhibitor and is used in biochemical assays to evaluate AChE activity and inhibitor potency; reported IC50 = 1.83 μM. Supplied as a powder for analytical and research use.
- Reversible acetylcholinesterase inhibitor with reported IC50 1.83 μM.
- High purity (99.7%) suitable for analytical applications.
- Suitable as a reference standard in biochemical and pharmacological assays.
- Powder form compatible with common laboratory solvents.
- Molecular formula C16H19NO3; molecular weight 273.33 g·mol⁻¹.
- Available in small quantities for research use.
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Medchemexpress LLC HY-104074 5mg Medchemexpress, Pocapavir CAS:146949-21-5 Purity:>98%
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Medchemexpress, HY-104074 5mg Pocapavir CAS:146949-21-5 Pocapavir is an investigational enterovirus (EV) capsid inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10408 2mg Medchemexpress, Ki20227 CAS:623142-96-1 Purity:>98%
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Medchemexpress, HY-10408 2mg Ki20227 CAS:623142-96-1 Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10622 10mg Medchemexpress, PF-00446687 CAS:862281-92-3 Purity:>98%
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Medchemexpress, HY-10622 10mg PF-00446687 CAS:862281-92-3 PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM. Pf-446687 is brain penetrant. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 10 MG
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AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It has shown a statistically significant reduction of PCP induced behavior in rats.
- Potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A)
- IC50 of 0.1 nM for phosphodiesterase 10A
- Statistically significant reduction of PCP induced behavior in rats
- Minimum effective dose of 0.3 mg/kg for efficacy in PCP-LMA model
- Exhibits a superior oral bioavailability of 72% in dogs
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Active Motif RVX-208
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Active Motif's RVX-208 is a potent BET bromodomain antagonist with (IC50 = 0.51 uM for BD2) with approximately 170-fold selectivity over BD1 (ref 1,2). It increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo, and it reduces atherosclerosis.
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eMolecules 5-Fluorothiazolo[4,5-b]pyridin-2-amine | 1206248-77-2 | MFCD14581837 | 100mg
Ambeed | 5-Fluorothiazolo[4,5-b]pyridin-2-amine | 100mg | 490539014 | A228450 | | 1206248-77-2 | MFCD14581837 | 169.180 | C6H4FN3S
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eMolecules Medchem Express / Hypidone (hydrochloride) / 2mg / 446256067 / HY-100769 / / 1339058-04-6 / MFCD30489758 / 334.840 / C18H23ClN2O2
Medchem Express / Hypidone (hydrochloride) / 2mg / 446256067 / HY-100769 / / 1339058-04-6 / MFCD30489758 / 334.840 / C18H23ClN2O2
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Medchemexpress LLC HY-U00076 1mg Medchemexpress, MK-0249 CAS:862309-06-6 Purity:>98%
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Medchemexpress, HY-U00076 1mg MK-0249 CAS:862309-06-6 MK-0249 is a potent histamine H3 receptor antagonist, with Ki of 1.7 nM for human H3. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-50098 5mg Medchemexpress, Mardepodect CAS:898562-94-2 Purity:>98%
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Medchemexpress, HY-50098 5mg Mardepodect CAS:898562-94-2 Mardepodect (PF-2545920) is a potent, orally active and selective PDE10A inhibitor with an IC50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect can cross the blood-brain barrier. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-103483 5mg Medchemexpress, MD2-IN-1 CAS:111797-22-9 Purity:>98%
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Medchemexpress, HY-103483 5mg MD2-IN-1 CAS:111797-22-9 MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 μM for the recombinant human MD2 (rhMD2). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10530 5mg Medchemexpress, Varlitinib CAS:845272-21-1 Purity:>98%
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Medchemexpress, HY-10530 5mg Varlitinib CAS:845272-21-1 Varlitinib (ARRY-334543; ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / GPNA (hydrochloride) / 10mg / 523883549 / HY-W011391 / / 67953-08-6 / MFCD00039054 / 303.700 / C11H14ClN3O5
Medchem Express / GPNA (hydrochloride) / 10mg / 523883549 / HY-W011391 / / 67953-08-6 / MFCD00039054 / 303.700 / C11H14ClN3O5
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